2 Aims

The aims of the thesis were to estimate the impact of PHiD-CV10 on

  1. The incidence of pediatric emergency department visits for otitis media with treatment failure (Paper I)
  2. The population-based incidence of otitis media visits in primary care (Papers II and VI)
  3. The population-based herd-effect on otitis media among unvaccinated children (Papers II and VI)
  4. The population-based incidence of outpatient antimicrobial prescriptions (Paper III)
  5. The population-based incidence of tymapnostomy tube procedures (Paper IV)
  6. The population-based incidence of hospitalizations for respiratory and invasive infections commonly associated with Streptococcus pneumoniae (Paper V)
  7. The population-based herd-effect on pneumonia hospitalizations among unvaccinated children and adults (Paper VI)
  8. The population-based herd-effect on hospitalizations for invasive pneumococcal disease among unvaccinated children and adults (Paper VI)
  9. The cost-effectiveness of introducing PHiD-CV10 into the pediatric vaccination program in Iceland (Paper VI)